- 学术论文
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Antibacterial polymeric nanostructures for biom...
Abstract:The high incidence of bacterial infection and the growing resistance of bacteria to conventional antibiotics have resulted in the strong need for the development of new generation of antibiotics. Nano-sized particles have been considered as novel antibacterial agents with high surface area and high reactivity. The overall antibacterial properties of antimicrobial nanostru...[详细]
2014-07-31 -
Polymer/TiO2 Hybrid Vesicles for Excellent UV S...
Abstract:Presented in this paper is a hybrid polymer/titanium dioxide (TiO2) vesicle that has excellent UV-screening efficacy and strong capacity to encapsulate antioxidant agents. Poly(ethylene oxide)-block-poly(2-(dimethylamino)ethyl methacrylate)-block-polystyrene (PEO-b-PDMAEMA-b-PS) triblock terpolymer was synthesized by atom transfer radical polymerization (ATRP) and then se...[详细]
2014-07-25 -
Asymmetrical Polymer Vesicles with a “Stealthy...
Abstract：The efficient intracellular drug delivery is an important challenge due to the slow endocytosis and inefficient drug release of traditional delivery vehicles such as symmetrical polymer vesicles, which have the same coronas on both sides of the membrane. Presented in this paper is a noncytotoxic poly(ethylene oxide)-block-poly(caprolactone)-block-poly(acrylic acid) (PEO1...[详细]
2014-07-07 -
Enzyme activated photodynamic therapy for methi...
AbstracIn recent years, methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most common multi-drug resistant bacteria in both hospital and community. The aim of this study is to investigate the selective inhibition of MRSA by a modified photosensitizer (LAEtNBS) in vitro and the efficacy of MRSA infection treatment by photodynamic therapy (PDT) with LAEtNBS in vivo....[详细]
2014-07-05 -
Preparation and Mechanism Insight of Nuclear En...
Abstract：The facile loading of sensitive and fragile biomacromolecules, such as glucose oxidase, hemoglobin, and ribonucleic acid (RNA), via synthetic vehicles directly in pure aqueous media is an important technical challenge. Inspired by the nucleus pore complex that connects the cell nucleus and the cytoplasm across the nuclear envelope, here we describe the development of a k...[详细]
2014-06-16 -
Progress in Syntheses and Applications of Polyp...
Abstract：Polypeptides and their hybrid copolymers have aroused much attention in biomedical fields due to their excellent biocompatibility and biodegradability. N-Carboxyanhydrides (NCA) can be polymerized into polypeptides and their hybrid copolymers via ring-opening polymerization with high efficiency and high yield. Also, polymers synthesized by this method have controlled chain length and ...[详细]
2014-06-05 -
How does a tiny terminal alkynyl end group driv...
Abstract：It is a theoretical and technical challenge to construct well-defined nanostructures such as vesicles from fully hydrophilic homopolymers in pure water. In this paper, we incorporate one terminal alkynyl group into a fully hydrophilic linear or non-linear homopolymer to drive its unusual self-assembly in aqueous solution to form multicompartment vesicles, spherical compound mi...[详细]
2014-05-06 -
Multifunctional Homopolymer Vesicles for Facile...
AbstractHomopolymers have been considered as a nonideal building block for creating well-defined nanostructures due to their fuzzy boundary between hydrophobic and hydrophilic moieties. However, this unique fuzzy boundary may provide some opportunities for fabricating functional nanomaterials. Presented in this paper is a pH-responsive multifunctional homopolymer vesicle based on ...[详细]
2014-04-07 -
Theranostic Vesicles Based on Bovine Serum Albu...
Abstract:Presented in this article is the preparation of a new theranostic vesicle which exhibits excellent in vitro and in vivo T1 magnetic resonance (MR) imaging contrast effect and good anticancer drug delivery ability. The theranostic vesicle has been easily prepared based on an amphiphilic biocompatible and biodegradable dibock copolymer, poly(ethylene glycol)-block-poly(l-la...[详细]
2014-04-01 -
Reduction of 4-nitrophenol catalyzed by silver...
AbstractWe report the reduction of 4-nitrophenol catalyzed by silver nanoparticles supported on polymer micelles and vesicles which can significantly improve the stability, dispersibility and catalytic activity of silver nanoparticles even at one ppm.文章链接：RSC Advances 2014, 4, 16425-16428. [详细]
2014-03-25 -
Effective oxidation protection of polymer micel...
Abstract：Copper nanoparticles are often susceptible to rapid oxidation in water. We report a water-dispersible and long-term stable copper nanoparticle protected by a block copolymer micelle that can effectively inhibit the access of oxygen to the copper inside its hydrophobic core, providing a sufficient diffusion barrier against oxidation in water.文章链接：RSC Advances 2014, 4, ...[详细]
2014-03-07 -