Antibacterial vesicles by direct dissolution of a block copolymer in water
作者：Cong Zhang, Yunqing Zhu, Chuncai Zhou, Weizhong Yuan and Jianzhong Du 时间：2012-09-25 点击数：
Abstract
A novel thermo- and pH-responsive antimicrobial
diblock copolymer
has been synthesized and directly dissolved in
water
to form
polymer
vesicles upon simply raising the temperature. Compared to individual polymer chains,
polymer
vesicles exhibit much better antimicrobial efficacy against both Gram-negative and Gram-positive bacteria under physiological conditions with neither quaternary ammonium moieties nor the loading of any external
antibiotics
as a result of their increased local concentration of cationic charge.
文章链接：Polymer Chemistry 2013, 4, 255-259.
