Abstract

Highly biocompatible pH-sensitive block copolymer vesicles can be prepared by the self-assembly of biocompatible block copolymers. Vesicle formation occurred spontaneously on adjusting the solution pH, with the hydrophobic chains forming the vesicle membrane and hydrophilic chains forming the vesicle coronas. The biocompatible vesicles can be used as drug carrier in pure water.

Keywords: Block copolymers; Vesicles; Self-assembly; Drug delivery

文章链接：Journal of Controlled Release 2011, 152, E16-E17.